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By P. Serra

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2009, Anderson et al. 2009). For example, electrochemical measurements based on impedance and capacitance are simple and inexpensive but need improved sensitivities for use with clinical samples (Wang 2006, Fernández-Sánchez et al. 2004). Resonant frequency changes of an anti-PSA antibody coated microcantilever enable a detection sensitivity of ~ 10 pg/ml but this micro-balance approach has issues with the effect of the solution on resonant frequency and cantilever damping (Fernández-Sánchez et al.

For example, electrochemical measurements based on impedance and capacitance are simple and inexpensive but need improved sensitivities for use with clinical samples (Wang 2006, Fernández-Sánchez et al. 2004). Resonant frequency changes of an anti-PSA antibody coated microcantilever enable a detection sensitivity of ~ 10 pg/ml but this micro-balance approach has issues with the effect of the solution on resonant frequency and cantilever damping (Fernández-Sánchez et al. 2004, Hwang et al. 2004).

The market size for prostate cancer testing is enormous. According to the American Cancer Society, prostate cancer is the most common form of cancer among men, other than skin cancer. It is estimated that during 2007, in the United States alone, 218,890 new cases of prostate cancer will be diagnosed and 1 in 6 men will be diagnosed with prostate cancer during his lifetime . The American Cancer Society recommends health care professionals to offer the prostatespecific antigen (PSA) blood test and the digital rectal exam (DRE) yearly for men above the age of 50.

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